SCIENTIST II, ANALYTICAL TECHNOLOGY

Job_Title: Scientist II, Analytical Technology
Employer_Name: Novartis
Web_Site: http://novartis.com
Contact_Name: Kenji Furuya
Contact_Email_Confirm: kenji_furuya@chiron.com
Business_Type: Industry
Job_Type: Research Scientist
Job_Country: US
Job_Location: Emeryville, CA

Background:


Duties:

Conduct the development and validation of a wide variety of analytical methods to support Novartis’ biopharmaceutical products development. Utilize multiple HPLC techniques including RP-HPLC, IEX-HPLC, and SEC-HPLC to determine the purity, impurity profiles, and degradation pathways of protein products. Employ other analytical techniques including peptide map, CE, SDS-PAGE, and UV-Vis spectroscopy to evaluate physicochemical property of products. Participate in the characterization of products and their variants using mass spectrometry, amino acid analysis, and N-terminal sequencing. Fully support commercial product and clinical product release testing by providing high quality of analytical methods, assay transfer, and troubleshooting. Generate reports for in-house and external submissions to regulatory agencies. Participate in multidisciplinary product development teams.

Qualifications:

Ph.D. in Chemistry, Biochemistry, or related discipline with emphasis in Analytical Chemistry with 3+ years of relevant experience, or BA/BS/MS with sufficient experience to afford Ph.D. level contribution. The candidate must have previous experience and technical proficiency with HPLC method. Familiarity with a wide range of protein analytical techniques including CE, UV-Vis spectroscopy, SDS-PAGE, light scattering, and mass spectrometry is essential. Practical experience with common protein chemistry techniques is also required. The candidate must possess strong interpersonal and verbal/written communication skills. The ability to function in a team environment is essential. Thorough understanding of GMP and quality concepts is desirable. The candidate is expected to have a good organizational skills and the ability to work effectively in a multi-project environment.
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